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All Services
Chemistry Services & High Potent Chemistry
Offering a state of the art manufacturing capabilities both at lab scale and commerical scale for proof of concept studies,
advanced intermediaries, bespoke GMP starting materials, NCEs/ APIs for pre-clinical and clinical trials and pro-dugs.
Our expertise lies in
Medicinal Chemistry
Library Synthesis
Feasibility Studies
Process R&D & Optimization
Impurity Profiling
Custom Systhesis
IP landscale Assessment Process Hazard
Evaluation
Key Technologies we use
Small scale and Large scale hydrogenation
Large scale chromatography Cryogenic
reaction
Metal mediated synthesis Flow chemistry
Solid phase synthesis High potent suites OEB 5
DoE
QbD MODDE software
High Potent Chemistry Capabilities
Toxins
We specialize in synthesizing linkers and designing of new linkers
- Hydrazones
- Peptides
- Disulphides
- Pegylated
- Thioethers
- Carbohydrates
Toxins
Isolated synthesis of Toxins using sem- syntheic
routes & employing dedicated preparative chromatography.
- Aurstatins
- Dolastatins
- Maytansines
- Calicheamicins
- Cuocarymycins
- PBD dimers
- α-amanitin
Linkers + Toxins
Linkers to Toxin conjugation expertise
ADCs, linkers, toxins
Peptide Chemistry
Carbohyd
rate Chemistry
rate Chemistry
Analytical Services
Analytical Method Development Analytical
Reference Standard
Isolation of impurity and characterization
Forced Degradation
Analytical Method Validation
Stability studies
Physicochemical property determination
Polymorphism studies Chiral Separation
Pertinent features
Pharmacopoeia: USP/NF, EP, BP, JP, ACS, AOAC and client-provided methods
State-of-Art instrumentation and facilities
Experienced scientists
Dedicated separation science lab
Flash chromatography system
Biotage with UV & ELSD detectors
Grace Reveleris with UV & ELSD detectors
Preparative HPLC systems
Gilson automated purification system
Discovery Biology
Molecular Biology
Toxins
Ames test
MIC
Time Kill PAE
MPC
In vivo studies
Outcome model(systemic infection)
Organ burden model(thigh/ lung infection)
Platform Technology
RT PCR studies
Gene expression analysis Cloning
Expression of recombinant protein
Novel Bacteriophages
Assay Biology
Chimerism analysis Genotox studies
Mitotox studies Antibiogram
Novel Bacteriophages
Preclinical Research
DMPK
Bioanalytical Research (BAR)
In Vivo Metabolism and Pharmacokinetics
In Vitro DMPK
Pharmacology
Oncology
Inflammation
Metabolic Disorder
Anti-infectives
Toxicology
General Toxicology
Genetic Toxicology
Pathology
Clinical chemistry and hematology lab